Who Classification Of Gestational Trophoblastic Disease

Who Classification Of Gestational Trophoblastic Disease

WHO Classification of Gestational Trophoblastic Disease

Gestational trophoblastic disease (GTD) is a group of rare tumors that develop in the cells that would normally form the placenta during pregnancy. These tumors can be benign or malignant and can have varying degrees of aggressiveness. To better understand and classify these diseases, the World Health Organization (WHO) has developed a classification system that helps healthcare professionals diagnose and treat GTD effectively.

The WHO classification of GTD is a comprehensive system that categorizes these diseases based on their histopathological features, clinical behavior, and genetic characteristics. This classification system allows for a more accurate diagnosis and helps guide appropriate treatment strategies.


Q: What are the different types of GTD?
A: The WHO classification recognizes several types of GTD, including complete hydatidiform mole, partial hydatidiform mole, invasive mole, choriocarcinoma, and placental site trophoblastic tumor.

Q: How does the WHO classification help in diagnosis?
A: The classification system provides clear criteria for diagnosing each type of GTD based on histopathological examination of tissue samples. This helps healthcare professionals differentiate between benign and malignant forms of GTD.

Q: How does the classification system guide treatment?
A: Each type of GTD has different treatment protocols. The WHO classification helps determine the appropriate treatment approach based on the specific diagnosis. For example, choriocarcinoma, a malignant form of GTD, often requires chemotherapy, while benign forms may only require monitoring or surgical intervention.

Q: Why is the WHO classification important?
A: The classification system ensures consistency in diagnosing and treating GTD worldwide. It allows for better communication among healthcare professionals and facilitates research and clinical trials to improve patient outcomes.

In conclusion, the WHO classification of GTD is a vital tool in diagnosing and treating these rare tumors. By providing clear criteria for diagnosis and guiding treatment strategies, this classification system helps healthcare professionals deliver the best possible care to patients with GTD.