Mothers using Antidepressants during pregnancy, have a slightly higher chance of giving birth to babies with a rare circulatory disorder.
Persistent Pulmonary Hypertension is a condition that affects blood pressure in the pulmonary capillaries, vein and artery. It can cause dizziness fainting and shortness of breath along with other symptoms. The survival rate of babies diagnosed with this condition can drop by up to 20 percent.
The study focused on information acquired from 3.8 million pregnancies comparing rates of PPHN occurrence in women on SSRI and non-users of antidepressants.
SSRI’s are Selective Serotonin Reuptake Inhibitors, and are defined as a class of compounds believed to increase the level of serotonin, typically used in various treatments, such as anxiety and depression. Medication containing SSRI’s includes some the most commonly prescribed type of antidepressants in the U.S.A.
Analysis was conducted by F. Huybrechts M.S .and Ph. D of Brigham and Women’s Hospital, Boston, along with some of her colleagues. The inquiry looked at data acquired between 2000-2010, collected in 47 states from Medicaid enrolled women.
The most commonly prescribed medicine used by the study subjects included Zoloft, Prozac and Paxil. It was found that the difference between users and non-users of SSRi’s, did not greatly affect chances of Infant Circulatory Disorder.
Overall out of 10000 births 31 infants were diagnosed with Circulatory disorders in the case of SSRI users and a close 29 cases were reported in the case of non-users.
Out of the entire study, totaling approximately 3.8 million women, 128, 950 women used antidepressant medication in the last quarter. 102.179 had contact with SSRI’s and a further 26.771 used a non SSRI antidepressant.
Antidepressants are recommended by many agencies and doctors in the United States as a first line step in the treatment for severe depression, and are also used for more mild depressions if they persist after treatment such as Cognitive Therapy.
Mothers take such antidepressants during pregnancy or after giving birth. In some cases due to stress, anxiety and depression, complications might occur.
Some speculation is increasing concerning use of SSRI’s during the breast-feeding period, and possible side effects for the infant, which could risk unwanted contact through the mother’s milk.
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