A recent study focused on the effects of ibuprofen on young men and found that this might lead to infertility issues. After taking the pills, even in average doses, a small sample of men developed a condition that causes male infertility. This condition is mostly present among middle-aged men.
The Unexpected Effects of Ibuprofen?
This new study is actually a continuation of previous research which monitored pregnant women. Through it, the experts wanted to see the effects of three mild pain relievers on pregnant women.
The pain relievers analyzed were paracetamol, aspirin, and ibuprofen. These experiments showed that all of these pills had an adverse effect on the testicles of male babies.
The authors of this latest study mentioned that all these three drugs disrupt male hormones. Namely, they affect the testicles, which secrete testosterone. This is the primary masculine sex hormone.
Another significant finding of the research indicated that male babies who were born from mothers who took any of these variants had a higher risk of congenital malformations.
After conducting these experiments, the scientists wondered what could happen to adult men when they took ibuprofen. They focused on this drug because it seemed to have the worst effects. Ibuprofen is commonly offered to athletes to prevent pain.
Researchers recruited 31 men as part of their study. The participants were in between 18 and 35 years old. Fourteen among them received a daily dosage of 1200 mg of ibuprofen. The other 17 participants received a placebo.
After just 14 days, the men who received ibuprofen presented lower levels of testosterone. In turn, this could lead to male infertility. Once there is a hormonal imbalance, this can cause a compensated hypogonadism.
This condition is associated with depression, male infertility, and a higher risk of strokes and heart failure. The researchers mentioned that the effects are reversible in the case of study participants. This is because they only used the drug for a short period of time. As it is, the long-term effects of using ibuprofen are still unknown.
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